Trigeminal Neuralgia (TN), also called tic douloureux, is a
chronic pain condition that affects the trigeminal nerve. The trigeminal
nerve is one of 12 pairs of nerves that are attached to the brain. The
nerve has three branches that conduct sensations from the upper, middle,
and lower portions of the face, as well as the mouth, to the brain.
Causes:
Depends upon the form of TN:
Medications
Surgery
Causes:
- Pressure: blood vessel(s) pressing on the trigeminal nerve as it exits the brain stem.
- Multiple sclerosis
- Nerve compression from a tumor
- Malformation of blood vessels
- Injury (sinus surgery, oral surgery, stroke, or facial trauma)
- Vibration or contact with the cheek (such as when shaving, washing the face, or applying makeup)
- Brushing teeth
- Eating
- Drinking
- Talking
- Even exposure to the wind
Depends upon the form of TN:
- typical or classic form (TN1): causes extreme, sporadic, sudden burning or shock-like facial pain that lasts anywhere from a few seconds to as long as two minutes per episode.
- atypical form (TN2): constant aching, burning, stabbing pain of somewhat lower intensity.
- Attacks stop for a period of time and then return
- The condition can be progressive
- Attacks can worsen over time
Medications
- Anticonvulsant medicines (antiseizure drugs)
- Tricyclic antidepressants
- Common analgesics and opioids
Surgery
- A rhizotomy (rhizolysis) is a procedure in which nerve fibers are damaged to block pain.
- Balloon compression works by injuring the insulation on nerves that are involved with the sensation of light touch on the face.
- Glycerol injection is also generally an outpatient procedure in which the individual is sedated with intravenous medication. The glycerol injection bathes the ganglion and damages the insulation of trigeminal nerve fibers.
- Radiofrequency thermal lesioning
- Stereotactic radiosurgery (Gamma Knife, Cyber Knife)
- Microvascular decompression (MVD)
- Neurectomy (partial nerve section)
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